This study aimed at investigating marginal bone loss influence on the biomechanics of single implant crown using finite element (FE) analysis. Four FE models for a 3.5 x 13 mm implant supported by 4 bone levels (8.5 mm, 10 mm, 11.5 mm, and 13 mm) were BMS202 subjected to 3 loading conditions: vertical, oblique, and horizontal. The results
indicated 5-10 times increase in maximum von Mises stresses under oblique and horizontal loading. The maximum stresses within the fixture were concentrated at the bone/fixture interface with highest value under horizontal loading at 10 mm bone support. Abutment screw was most susceptible to fracture as the highest stress was concentrated at the screw/fixture interface. Cortical bone suffered its greatest stress level at the fixture/bone interface at 10 mm bone support. However, increasing bone support to 11.5 mm has improved the fracture resistance of the abutment screw to a great extent especially under oblique and vertical loading. Severe marginal bone loss might be attributed for abutment screw and fixture head fracture especially under horizontal loading.”
“Purpose: To determine whether previous transurethral resection of the prostate
(TURP) compromises the surgical outcome and pathologic findings in patient who underwent either radical robot-assisted S3I-201 JAK/STAT inhibitor laparoscopic prostatectomy (RALP) or open retropubic radical prostatectomy (RRP) after TURP, because TURP is reported to complicate radical prostatectomy and there are conflicting data.
Patients and Methods: From July 2008 to July 2010, 357 patients underwent RALP. Of these, 19 (5.3%) patients had undergone previous TURP. Operative and perioperative data of patients were compared with those of matched controls selected from a database of 616 post-RRP patients. Matching criteria were age, clinical stage, the level of preoperative prostate-specific-antigen, the biopsy Fedratinib nmr Gleason score, the American Society of Anesthesiologists classification score, and prostate volume assessed during transrectal ultrasonography. All RRP and RALP procedures were performed by experienced surgeons.
Results: Mean
time to prostatectomy was 67.4 months in the RALP group and 53.1 months in the RRP group. Mean operative time was 217 +/- 51.9 minutes for RALP and 174 +/- 57.7 minutes for RRP (P < 0.05). The overall positive surgical margin rate was 15.8% in both groups (pT(2) tumors: 10.5% for RALP and 5.3% for RRP; P = 1.0). Mean estimated blood loss was 333 +/- 144 mL in RALP patients and 1103 +/- 636 mL in RRP patients (P < 0.001). The difference between preoperative and postoperative hemoglobin levels was 3.22 +/- 0.98 g/dL for RALP and 5.85 +/- 1.95 g/dL for RRP (P = 0.0002). The RALP and RRP groups also differed in terms of hospital stay (8.58 +/- 1.17 vs 11.74 +/- 5.22 days; P = 0.0037), duration of catheterization (7.95 +/- 5.69 vs 11.78 +/- 6.97 days; P = 0.