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2009 Wiley Periodicals, Inc. J Appl Polym Sci 115: 3303-3310, 2010″
“Cerebral cavernous malformations (CCMs) are vascular abnormalities that may cause seizures, headaches, intracerebral hemorrhages, and focal neurological deficits; they can also be clinically silent and may occur as a sporadic or an autosomal dominant condition. Three genes have been identified as causing familial CCM: KRIT1/CCM1, MGC4607/CCM2, and PDCD10/CCM3, mapping, respectively, on chromosomes 7q, 7p, and 3q. This is a report Sapitinib nmr on an Italian family affected by CCM due to a KRIT1 gene mutation on exon 13. The mother suffered from a cerebellar hematoma and was severely disabled; one son had suffered from intractable seizures and underwent surgery

for removal selleck chemical of a cavernous angioma, while another son was asymptomatic. Brain MRI showed CCMs in all patients. This report underlines that a familial form of CCM could be suspected when a patient presents with multiple CCMs; neurologists and neurosurgeons should be aware that genetic testing for these forms is available.”
“Interest exists in the manufacture of functional meat products whereby synthetic antioxidants are replaced with naturally-sourced compounds. Therefore the aim of this study was to determine the bioactivity of pork and beef patties containing ellagic acid (600 mu g/g), lutein (200 mu g/g) or sesamol (500 mu g/g). Cooked pork and beef patties were subjected to an in vitro digestion procedure and the resultant micelles were added to human intestinal Caco-2 cells. Supplementation with micelles from lutein-enriched pork patties protected (P < 0.05) against H(2)O(2)-induced cell injury whereas the presence of control beef, lutein-enriched beef or ellagic acid-enriched beef, at levels >= 20% (v/v), enhanced (P < 0.05) oxidant-induced cytotoxicity. None of the pork patties significantly BEZ235 modulated cellular

glutathione content. Micelles from all the enriched pork patties significantly protected against H(2)O(2)-induced DNA damage. In conclusion, the cytoprotective and genoprotective effects of ellagic acid, lutein, and sesamol, when incorporated into meat systems, depend greatly on the food matrix. (C) 2009 Elsevier Ltd. All rights reserved.”
“The radio-frequency plasma-initiated polymerization of N-isopropylacrylamide (NIPAM) in the solid state was performed. The isolated linear polymer was characterized by (13)C-NMR, (1)H-NMR, and Fourier transform infrared spectroscopy, and the effects of selected operational plasma parameters (discharge power and time) on the conversion rates were studied. Reversible transitions at the volume-phase-transition temperatures of the swelled poly(N-isopropylacrylamide) hydrogels were investigated by differential scanning calorimetry. The surface morphologies before and after plasma treatment were followed by scanning electron microscopy.