Two cases of Castleman’s disease (1 abdominal and 1 retroperitoneal) were confirmed histopathologically. The clinical and medical imaging features were described and relative literatures were reviewed.
One patient GPCR Compound Library concentration had no clinical symptoms and the other had epigastric discomfort. The location of the benign tumor was retroperitoneal and left adrenal gland, respectively. Both cases were of solitary tumor, 1 was a hyaline-vascular type and the other was a mixed type with plasma cell and hyaline-vascular type. Both were successfully treated by surgical excision. Patients were followed up for 3 and 4 years respectively
with no signs of recurrence on CT imaging.
Abdominal Castleman’s disease lacks specific clinical manifestations. Definitive diagnosis requires histologic examination and excisional surgery is the method of choice for treatment.”
“The incidence of hepatocellular carcinoma (HCC) in Mongolia is far higher than that of any other cancer in the country, and among the highest worldwide. The relative importance of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is unclear. We reviewed (i) medical records for 963 patients with HCC and 941 patients with cirrhosis admitted for the first time to the National Cancer Center of Mongolia and the National Center for Communicable
Diseases, respectively, from 2000 to 2009, and (ii) articles published from 1990 to 2010 on the seroprevalence of hepatitis B surface antigen (HBsAg) and antibodies against hepatitis C virus (anti-HCV) CYT387 molecular weight among individuals with and without liver disease. Among those with HCC, the seroprevalence of HBsAg, anti-HCV and dual infections was 50, 27 and 21%, respectively. Corresponding percentages among the
patients with cirrhosis were 40, 39, and 20%. In both diseases, see more HCV infection was relatively more prevalent in women than in men and, in cirrhosis, in patients older than 45 years of age. In healthy individuals, from published articles, anti-HCV seroprevalence steadily increased with age (from 3% at age 0-5 years to 34% at age >= 50 years), whereas HBsAg seroprevalence stayed constant at about 8%. The future benefit of childhood vaccination against HBV in Mongolia will be undermined by the consequences of a severe HCV epidemic and a uniquely high burden of dual infections. European Journal of Cancer Prevention 20:33-39 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“Colorectal polyps are usually asymptomatic and are found opportunistically. Individuals with adenomata are at increased risk for cancer and therefore guidelines exist for surveillance of these lesions including those of the British Society of Gastroenterology (BSG). Deviation from these guidelines is common and increases the workload of endoscopy. We examined those individuals waiting for endoscopy for polyp surveillance to see whether strict adherence to BSG guidelines could facilitate opportunities for screening.