This research generated algorithms for translating

SDQ scores to utility values and providing researchers with an additional tool for conducting health economic evaluations with child and adolescent mental health data.”
“Introduction and objectives. The mechanisms that trigger ventricular fibrillation (VF) are poorly understood. The aim of this study was to analyze the initiation of VF in electrograms stored in implantable cardioverter-defibrillators (ICDs).

Methods. We analyzed ICD electrograms from patients who had suffered at least one episode of VF.

Results. Of 250 patients with ICDs, 13 (10 male and 3 female, age 49 22 years) had at least one episode of VF. The diagnoses were Brugada syndrome (n=4), ischemic heart disease (n=3), dilated cardiomyopathy (n=2), hypertrophic Selleckchem BX-795 cardiomyopathy (n=1), short-coupled variant of torsades de pointes (n=1), endocardial fibroelastosis PD98059 datasheet (n=1) and idiopathic

VF (n=1) In 7 patients, VF was the reason for ICD implantation Overall, 31 episodes of VF were recorded, including three episodes of arrhythmic storm In the 7 patients who had more than one episode of VF (within minutes or up to 3 years apart), all episodes started with premature ventricular complexes (PVCs) that had the same morphology and similar coupling intervals. A short-long-short cycle was observed in 2 patients In 21 episodes, PVCs that did not trigger VF were observed during sinus rhythm There was no significant difference between them and PVCs that did

trigger VF in terms of morphology, coupling interval (409 +/- 121 ms vs 411 +/- 123 ms) or the preceding sinus rhythm RR interval (801 +/- 233 selleck products ms vs 793 +/- 230 ms)

Conclusions. Spontaneous VF in the form of an arrhythmic storm or an isolated episode were triggered by PVCs On occasions, PVCs preceded VF without triggering it.”
“Methods: We examined the medical records of patients with LVEF < 35% and COPD and analyzed the data for total mortality by ICD status. Each ICD patient was matched by age and LVEF with two to three controls. The Charlson comorbidity index and propensity score were used to correct for differences in comorbidities and biases between the study groups.

Results: A total of 100 patients (30 with ICD and 70 controls) were included in this analysis. The overall cohort had a mean age of 65 +/- 15 years with a predominance of white (79%) men (72%). Compared to controls, ICD patients had a wider QRS complex (150 +/- 32 ms vs 110 +/- 24 ms, P < 0.001) and were less likely to be on steroid therapy (10% vs 31%, P = 0.018) for COPD. At a mean follow-up of 3.1 +/- 2.7 years, ICD patient had a lower total mortality (2-year survival of 88% in the ICD group vs 59% in the controls, P = 0.016). The lower death rate in the ICD group persisted after correcting for differences in the QRS interval and for discrepancies race and in the incidence of steroid use in a multivariate Cox regression model (odds ratio = 0.300, adjusted P = 0.016).