Furthermore, the changes in the liver enzymes and bilirubin before and after this website surgery were compared with history of diabetes, history of myocardial infarction, and intra-aortic balloon pump use via the multiple regression test, which revealed no significant relationships

(P=0.22 for diabetes, P=0.82 for myocardial infarction, and P=0.27 for intra-aortic balloon pump). Table 2 Liver function test indices before and after Inhibitors,research,lifescience,medical surgery (mean±SD) Table 3 Relationship between the changes in the liver function tests with respect to sex, history of diabetes, history of myocardial infarction, and use of intra-aortic balloon pump, before and after surgery (mean±SD) Table 4 Relationship between the liver function tests and the number of infused packed blood cell units, before and after surgery (mean±SD) There were no significant differences between the Inhibitors,research,lifescience,medical changes in the liver function tests

and age, Body Surface Area, hematocrit, and lowest hematocrit level of the patients during surgery (the Pearson correlation coefficient test). The creatinine level showed a reverse significant correlation with the mean indirect bilirubin changes (P<0.05). However, it did not have any correlation with the mean changes in the other hepatic enzymes (P>0.05). The Inhibitors,research,lifescience,medical ejection fraction had a significant reverse correlation with the mean ALP changes (P<0.05), and it did not have a significant correlation with the other liver function tests (table 5). Table 5 Correlation between the liver function tests and the studied quantitative variables,

before and after surgery (mean±SD) The CVP had a direct and significant relationship with the mean ALT and AST changes (P<0.05). Moreover, CPB time had a direct and significant Inhibitors,research,lifescience,medical relationship with the mean direct and indirect bilirubin and AST (P<0.05), whereas it had no significant correlation with the changes in the ALT and ALP levels. The aortic cross-clamp time only showed a direct significant relationship with AST (table 5). In this study, all the patients received inotrope and vasopressors until the first postoperative Inhibitors,research,lifescience,medical day. None of the patients had a history of cerebral vascular disease. Discussion For all the recent advances in the techniques and modes of anesthesia in on-pump cardiac surgery, liver complications still remain one of the most Org 27569 severe postoperative consequences of cardiac surgery. Although it is believed that a lower hemoglobin level in women, small stature, and age-related atherosclerosis can affect the perfusion of visceral organs,2 we found no significant relationship between the changes in the liver function tests and age, sex, and Body Surface Area. During on-pump cardiac surgery, even with mild hypothermia, the basal metabolic rate is decreased. Hypothermia helps the individual to tolerate low hematocrit because of hemodilution.