Design: Dietary intakes of n-3 and n-6 PUFAs, plasma concentrations

of total and HDL cholesterol, and rs174546, rs482548, and rs174570 in the FADS gene cluster region were measured in 3575 subjects in the second survey of the Doetinchem Cohort Study.

Results: Significant associations between rs174546 genotypes and total and non-HDL-cholesterol concentrations were observed in the group with a high intake of n-3 PUFAs (>= 0.51% of total energy; P = 0.006 and 0.047, respectively) find more but not in the low-intake group (P for interaction = 0.32 and 0.51, respectively). The C allele was associated with high total and non-HDL-cholesterol concentrations. Furthermore, the C allele was significantly Sonidegib price associated with high HDL- cholesterol concentrations in the group with a high intake of n-6 PUFAs (>= 5.26% of total energy, P = 0.004) but not in the group with a low intake (P for interaction = 0.02).

Conclusion: Genetic variation in the FADS1 gene potentially interacts with dietary PUFA intakes to affect plasma cholesterol concentrations, which should be investigated further in other studies. Am J Clin Nutr 2010;92:258-65.”
“The relationships between the material parameters, i.e., the fiber fineness, porosity, areal density,

layering sequence, and airflow resistivity with the normal-incidence sound absorption coefficient of nonwoven composites consisting of three layers have been studied. The monofiber or multifiber needle-punched nonwovens included poly(lactic acid) (PLA), polypropylene (PP), glass fiber, and hemp fibers. Air flow resistivity

was statistically modeled and was Foretinib Protein Tyrosine Kinase inhibitor found to increase with decreasing fiber size and nonwoven porosity. The former models developed for glass fiber mats in the literature were found to be inconsistent with the air flow resistance of the nonwovens reported below. The effects of the layering sequence on air flow resistivity and sound absorption were obtained. It was found that when the layer including reinforcement fibers, i.e., hemp or glass fiber, faced the air flow/sound source, the air flow resistance and the absorption coefficient were higher than the case when the layer including reinforcement fibers was farthest from the air flow/sound source. The difference was more pronounced if there was a greater difference between the resistivity values of the constituent layers of the nonwoven composite. Sound absorption coefficient was statistically modeled in terms of air flow resistivity and frequency. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 3056-3069, 2011″
“As a fundamental study of thermally assisted recording, remanence coercivity at recording speed and the energy barrier for magnetization switching for granular media were evaluated as a function of temperature T.