2. Materials kinase inhibitor Wortmannin and Methods 2.1. Proposed System In our proposed system, the pelvis was topographically divided into two midline zones (zone I & II) and two paired (right and left) lateral zones (zone III & IV). Zone I is the area between the two round ligaments from their origin at the uterine cornua to their insertion in the deep inguinal rings. Zone II is the area between the two uterosacral ligaments from their origin from the back of the uterus to their insertions in the sacrum posteriorly. Zone III is the area between the uterosacral ligament inferiorly and the entire length of the fallopian tube and the infundibulopelvic ligament superiorly. Zone IV is the triangular area lateral to the fallopian tube and the infundibulopelvic ligament and medial to the external iliac vessels up to the round ligament (Figure 1).

The contents of the different zones are shown in Table 1. Figure 1 A color-coded illustration of the anatomical boundaries and the contents of all pelvic zones. Table 1 Descriptive summary of the anatomical boundaries and the contents of each pelvic zone. 2.2. Retrospective Evaluation of Dictated Reports This study was conducted at the University Hospitals Case Medical Center (UHCMC), Case Western Reserve University, Cleveland, Oh, USA. After IRB approval was obtained, operative reports of 540 patients who underwent diagnostic or operative laparoscopy for the diagnosis of unexplained infertility between January 2005 and January 2012 were collected. The operative reports for these patients were reviewed with allocation of the reported positive or negative findings to the respective zones as shown above.

All reports were evaluated for the comprehensiveness of the description with respect to normal findings or pathology for six zones as follows. Using this mapping of the pelvis, the operative reports were reviewed for completeness in description of anatomical findings. Descriptive statistics are presented. 3. Results During the review period of the study, 8876 laparoscopies and hysteroscopies were performed within the entire UHCMC system for a variety of indications. Of these, a total of 540 cases of diagnostic and/or operative laparoscopy with and without hysteroscopy for unexplained infertility were identified. These cases were selected as they are usually intended as a careful surveillance of pelvic anatomy in order to identify an etiology of infertility.

As the goal of these surgical cases is the identification of anatomy, it was thought fit that these operative reports would focus on the description of anatomy. All operative reports commented on the uterus, tubes, and ovaries (100%), which reflect parts of zone I and part of zone III. Only AV-951 17% (n = 93, 95% CI: 13.8�C20.2) commented on the dome of the bladder and the anterior cul-de-sac (the remainder of zone I). Twenty-four percent (n = 130, 95% CI: 20.4�C27.6) commented on the posterior cul-de-sac, which represents part of zone II.