065 for intervention when controlling for contemplation ladder and .055 when controlling for gender). Change in Motivation The repeated measures ANOVAs (Table 2) revealed increases over time in motivation (Contemplation Ladder, p < .001; TAA Desire, p < screening library .001) and self-efficacy (TAA Success, p = .008), but not perceived difficulty of staying abstinent (TAA Difficulty, p = .942). These changes were similar for both intervention groups (p��.247 for the interactions of intervention group by time for all three variables). At the 3-month follow-up, 17.9% of the sample identified quitting for good as their goal, with no difference by intervention group (p = .999). Among those abstinent at the 3-month follow-up, three of nine identified sustained abstinence as their goal. Table 2.
Repeated Measures Analysis of Variances Testing the Main Effect of Changes Over Time in Motivation and Self-efficacy and the Interaction of Changes Over Time by Intervention Condition (p values) Quit Attempts and Engagement in More Intensive Cessation Treatment Most participants reported trying to reduce or quit smoking between the counseling intervention and 3-month follow-up with no significant difference by group: 94.7% HTO versus 85.7% HTS (p = .607). The data suggested that more HTS (28.6%) than HTO (5.3%) participants sought intensive cessation treatment (p = .095). For both interventions all of those who were abstinent at the 3-month follow-up reported quitting cold turkey.
Smoking Reduction At the 3-month follow-up, the change in cigarettes smoked in the past seven days among those who were still smoking was comparable for the two groups: HTS median change = 0 cigarettes/week (IQR = ?2 to +6) and HTO median change 0 (IQR = ?3 to +10; p = .634). The treatment effect was on quitting, not on reduction of cigarettes per week among continuing smokers. Intervention Acceptability Ratings Participant ratings of acceptability of the intervention videos did not vary significantly by group (p �� .360). On 10-point scales where 10 was the strongest positive valence and 0 the lowest, the subjects independent of intervention had a mean of 6.48 �� 2.80 (SD) for liking the videos, 7.44 �� 1.96 for familiarity with the content, and 4.65 �� 3.01 for degree of new information learned from the videos. In both groups, 31% of participants (8 per group) reported the videos made them feel uncomfortable.
Participants who were abstinent at the 3-month follow-up reported liking the videos at baseline more than participants who were still smoking (8.22 �� 1.86 vs. 6.16 �� 2.77, p = .043). Familiarity, new information, and discomfort ratings did not predict abstinence status. Discussion This paper reports the first Anacetrapib randomized trial of using counseling about SHS (HTO) as a cessation method for adult nondaily smokers.