001 Cytoplasmic E- Amino acid transport and metabolism 5 gi|1245379 glnA Glutamine synthetase I Sinorhizobium meliloti 5.2/5.33 52287/61000 2.92 ± 0.08 0.001 Cytoplasmic 6 gi|15887731 argB Acetylglutamate kinase Agrobacterium tumefaciens 5.16/5.41 31083/30000 2.19 ± 0.09 0.001 Cytoplasmic 7 gi|89258357   Putative periplasmic substrate binding protein Ochrobactrum anthropi 5.84/5.78 28188/24000 ↑1.00 – Periplasmic 8 gi|222109054 nocP Opine permease ATP-binding protein Agrobacterium find more radiobacter 6.98/5.22 28288/20000 ↑1.00 – Inner Membrane 9 gi|222087066 pepF Oligoendopeptidase F protein Agrobacterium radiobacter 5.32/5.33 68989/76000 ↑1.00 – Cytoplasmic 10 gi|222087908 asd Aspartate-B-semialdehyde dehydrogenase protein Agrobacterium

radiobacter 5.46/5.59 37925/45000 1.38 ± 0.043 0.001 Cytoplasmic 11 gi|222084786 argD Diaminobutyrate–pyruvate aminotransferase protein Agrobacterium radiobacter 5.63/6.35 Ispinesib concentration 42909/43000 ↑1.00 – Cytoplasmic 12 gi|114765810 ilvE Branched-chain amino acid aminotransferase Pelagibaca bermudensis 5.31/5.68 32142/35000 ↑1.00 – Cytoplasmic F- Nucleotide transport and metabolism 13 gi|86146888 pyrH Uridylate Kinase Vibrio sp. 5.08/5.82 26284/33000 1.38 ± 0.13 0.008 Cytoplasmic G – Carbohydrate transport and metabolism 14 gi|222085874 eno Phosphopyruvate hydratase Agrobacterium radiobacter 4.84/4.95 45120/53000 2.88 ± 0.37 0.005 Cytoplasmic 15 gi|282887091

  Alpha amylase catalytic region Burkholderia sp. 6.26/5.03 64245/34000 ↑1.00 0.001 Cytoplasmic 16 gi|241206422   Transaldolase Rhizobium leguminosarum 5.32/6.12 35091/29000 ↑1.00 – Cytoplasmic 17 gi|11493200 pgm Phosphoglucomutase Rhizobium tropici SGC-CBP30 molecular weight 5.16/5.38 58641/72000 ↑1.00 – Cytoplasmic 18 gi|222084905 aglA Alpha-glucosidase protein Agrobacterium radiobacter 4.84/4.86 62592/65000 ↑1.00 – Cytoplasmic H – Coenzyme transport and metabolism 19 gi|222086485   ABC transporter Agrobacterium radiobacter 5.23/5.21 38975/42000 1.70 ± 0.09 0.001 Periplasmic 20 gi|296105270   Biotin protein ligase Enterobacter cloacae 5.23/5.42 35255/28000 3.98 ± 0.24

ADAMTS5 0.001 Cytoplasmic I – Lipid transport and metabolism 21 gi|299768808   Acyl-coa dehydrogenase Agrobacterium tumefaciens 5.37/4.66 65994/40000 ↑1.00 – Cytoplasmic 22 gi|282888281   3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain protein Burkholderia sp. 6.27/5.74 38552/35000 ↑1.00 – Cytoplasmic 23 gi|159186213 pcaF Beta-ketoadipyl coa thiolase Agrobacterium tumefaciens 5.51/6.37 41850/46000 2.95 ± 0.07 0.001 Cytoplasmic P – Inorganic ion transport and metabolism 24 gi|222087891 bfr Bacterioferritin Agrobacterium radiobacter 4.81/4.94 16860/19000 2.27 ± 0.07 0.001 Cytoplasmic 25 gi|87199081   Tonb-dependent receptor Novosphingobium aromaticivorans 5.82/5.01 87810/75000 ↑1.00 – Extra Cellular Cellular processes and signaling D – Cell cycle control, cell division, chromosome partitioning 26 gi|222086436 ftsZ2 Cell division protein Agrobacterium radiobacter 5.21/5.39 63014/81000 2.42 ± 0.26 0.